5 Simple Techniques For https://www.ceesdekker.net

5 Simple Techniques For https://www.ceesdekker.net

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Nanotechnology delivers A selection of alternatives to add to biology. Here I will present examples exactly where nanofabrication – the chance to make confined constructions with dimensions at will – is applied to look at the biophysics of one molecules and cells. I'll current some illustrations from our lab:

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I am able to rarely consider how I, being a geneticist, would be capable to understand basic physics, let alone contend at the best. How did you go over it?

2010, produced a whole new way (‘wedging transfer’) to govern nanostructures; to start with report of DNA translocation through graphene nanopores; and realized hybrid nanopores by directed insertion of α-hemolysin into sound-condition nanopores

SMC complexes can move Bodily roadblocks bigger than their ring dimension, indicating a nontopological mechanism for DNA loop extrusion

We use nanofabricated microfluidic constructions to pattern spatial boundaries for bacteria and biomimetic vesicles with reconstituted protein networks and this evaluate the basic purpose of spatial confinement for the molecular and mobile degree. Our assignments incorporate the next:

2000, discovery that nanotubes can carry amazing large recent densities; fixed the controversial problem of electronic transportation through DNA molecules by measurements of insulating conduct at The only molecule amount; and demonstration of an AFM approach for solitary-molecule manipulation of nanotubes

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But carbon nanotubes have remained a investigate subject matter of appreciable fascination to a lot of. In truth, the cees dekker outlook on working with carbon nanotubes to develop functional units, in places like radio-frequency electronics, digital electronics and versatile electronics, stays vivid.

Due to the fact 2000 he moved to single-molecule biophysics and nanobiology, with investigate from reports of DNA loop extrusion and supercoiling to DNA translocation via nanopores. Extra just lately his research has centered on studying chromatin framework and mobile division with microorganisms on chip, while he can be attempting to in the long run Develop artificial cells from The underside up.

Nanoscientist Cees Dekker is undoubtedly an amiable and flamboyant gentleman who appears A great deal young as opposed to 62 many years he actually is – modern glasses, psychedelic shirt, engaging smile – although not one particular to waste time. He usually takes his time, but not more than essential.

2008, 1st observation of protein-coated DNA translocation by way of nanopores; solved the origin on the electrophoretic power on DNA in nanopores; identified a substantial velocity improve of microtubules in electric fields; discovered an anomalous electro-hydrodynamic orientation of microtubules; and fixed the origin of sounds in carbon nanotubes in liquid

2013, controlled shaping of Stay bacterial cells into arbitrary shapes; and discovery of spontaneous fluctuations from the handedness of histone tetrasomes